Carl Sagan suggested “it would be wryly interesting if, in human history, the cultivation of marijuana led generally to the invention of agriculture and thereby to civilization.”
Carl Sagan’s reflection (Sagan, 1971) captures the enduring and complex relationship between Cannabis sativa and humanity. Sagan’s dryly humorous speculation alludes to a deeper truth: Cannabis has long occupied a unique niche at the intersection of plant evolution, human culture, and ecological function. But beyond its storied cultural and agricultural history lies a less explored question: How does the phytochemical composition of Cannabis mediate ecological interactions—particularly with arthropods—and how is it shaped by evolution, environment, and human intervention?
Carl Sagan’s reflection (Sagan, 1971) captures the enduring and complex relationship between Cannabis sativa and humanity. Sagan’s dryly humorous speculation alludes to a deeper truth: Cannabis has long occupied a unique niche at the intersection of plant evolution, human culture, and ecological function. But beyond its storied cultural and agricultural history lies a less explored question: How does the phytochemical composition of Cannabis mediate ecological interactions—particularly with arthropods—and how is it shaped by evolution, environment, and human intervention?